King Saud University Gene Mutation Worksheet Below is the DNA base sequence for the normal protein for normal hemoglobin and the base sequence for (abnormal) sickle cell hemoglobin Gene Mutation Worksheet
(5 marks)
Below is the DNA base sequence for the normal protein for normal hemoglobin and the base sequence for
(abnormal) sickle cell hemoglobin:
Normal gene: GGG CTT CTT TTT
Sickle gene: GGG CAT CTT TTT
A. Transcribe and translate the normal and sickle cell DNA sequences
above.
mRNA codon sequence: normal:
Sickle:
amino acids coded:
normal:
Sickle:
B. What kind of a gene mutation is this?
mRNA Codon decoder grid:
4
Gene Mutation Worksheet
(5 marks)
Below is the DNA base sequence for the normal protein for normal hemoglobin and the base sequence for
(abnormal) sickle cell hemoglobin:
Normal gene: GGG CTT CTT TTT
Sickle gene: GGG CAT CTT TTT
A. Transcribe and translate the normal and sickle cell DNA sequences
above.
mRNA codon sequence: normal:
Sickle:
amino acids coded:
normal:
Sickle:
B. What kind of a gene mutation is this?
mRNA Codon decoder grid:
4
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