Imagine that, in hypothetical study shown in table below, cases underestimated their exposure and, as a result, 20% of exposed cases were falsely categorized as unexposed, however that the classification of controls was not affected.
True results of the hypothetical case-control study with no measurement Error.
|
| Cases | Controls | Total |
| Exposed | 300 | 250 | 550 |
| Unexposed | 100 | 150 | 250 |
| Total | 400 | 400 | 800 |
Explain whether this type of misclassification random or systematic? Is it differential or nondifferential?
b) What effect would it have over the results of study? Draw up a two-by-two table displaying the misclassification, then determines estimates of the risk ratio for both true and the misclassified results and make comment on their difference to illustrate the effect.
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