Muscle contraction experiment

Muscle contraction experiment: Use the following list and any supplies you have around your house/office to simulate the following steps and stages of muscle contraction. You can draw portions of the neuron and muscle on a large piece of paper. On the piece of paper, you should have a key of which materials are which in your simulation. You should have calcium, sodium, acetycholine, receptors channels, actin, myosin, and ATP. Be creative with this. You can make it with stages, or have the entire process in front of you. You need to or do a series of pictures to show the steps.

Simulate the following steps:

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1. Action potential sent down the axon opening a calcium channel allowing for an influx of calcium into the presynaptic terminal.

2. Release of acetylcholine into the synaptic cleft.

3. Acetylcholine contacts protein channel in the membrane of the muscle cell and opens allowing for an influx of sodium into the muscle cell.

4. Depolarization of the muscle allows for calcium release from the sarcoplasmic reticulum.

5. Calcium in the sarcoplasm attaches to troponin and moves the tropomyosin away from the active sites in the actin.

6. Use and breakdown of ATP to move the myosin head to form a cross-bridge, move the actin, and release back to the original position.

7. After contraction, calcium is actively transported back into the sarcoplasmic reticulum. Releasing the troponin and restoring the troponin-tropomyosin complex back to the original position.

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