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Week 4-Cytoxan- Mitosis, Meiosis and cancer Ricardo Montalvo posted Nov 11, 2019 10:48 PM

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BIOL 103 7990 Introduction to Biology (2198) SK

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Cancer is like an uncontrolled mitosis. In Mitosis the cell replicates themselves and creates two

identical copies from the original so is a controlled process. Cancer is an uncontrolled growth

and division of cells.

Cytoxan, (Generic Name: Cyclophosphamide), is a drug use to treat: Hodgkin’s and non-

Hodgkin’s lymphoma, Burkitt’s lymphoma, chronic lymphocytic leukemia (CLL), chronic

myelocytic leukemia (CML), acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL),

t-cell lymphoma (mycosis fungoides), multiple myeloma, neuroblastoma, retinoblastoma, breast

cancer, ovarian cancer, and conditioning regimens for bone marrow transplantation. This drug

is designed to work during the rest cycle of the cell and before the growing phases and

mitosis. The Drug is classified as an alkylating agent which are most active in the resting phase

of the cell. The drug work by damaging the RNA or DNA that tells the cell how to copy itself

in division. Most common side effects are: Low blood counts, hair loss, nausea and vomiting,

poor appetite and discoloration of the skin and nails.

Reference:

Chemocare, Cytoxan. Retrieved 11 November 2019, from

http://chemocare.com/chemotherapy/drug-info/cytoxan.aspx