Solution-Analysis of the patients serum cortisol level | Homework Help

Charley shows up at his doctors office complaining of a feeling of weakness, which is getting worse, chronic fatigue and loss of appetite. His weight compared to that of 6 months ago is down about 10 pounds. He denies dieting. After obtaining a complete history, Charley’s physician performs three tests.

1. Analysis of the patients serum cortisol level shows the level is below normal.

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2. Synthetic CRH is injected IV the serum collected after this again reveals cortisol levels below normal.

3. Cosyntrin, a synthetic ACTH is injected IV, the serum collected afterwards shows normal levels of Cortisol. Explain where the problem specifically is located. Using the above test results (numbered 1-3) as proof of your answer. Go through each step (1-3) showing what each step proves.

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