pharmaceutical drug whose synthesis is at least 6 steps
Please select a pharmaceutical drug (legal), whose synthesis is at least 6 steps. Do not choose from “biologics”, which means antibodies, dna, peptides that are produced from cells or other biological sources. Please report on the following
The report should have the following sections: (i) title, including your name, email, and student id. Do not put on a separate page. (ii) Abstract (75 word limit), (iii) Introduction (discuss history of disease that the drug addresses and how people are affected, strategies used to combat disease that existed prior to the drug you are reporting on), (iv) results: how the drug was discovered, who is the commercial vendor and yearly sales, its biological mode of action, side effects, how it is prepared. This last and most important part should include your synthetic scheme, and separate schemes for mechanisms of the steps that use mechanisms we have learned in class. Your report must contain at least 1 mechanistic scheme. You are encouraged to use any other figures, charts, or tables that help support your discussion. All schemes must be drawn with chemdraw or similar software. Hand drawn schemes will not be accepted. (v) conclusions – summarize findings and outlook (do we need new drugs? What is the problem with this drug). (vi) references.
The references will need to include the journal article where the synthesis was originally reported and where the compound was originally discovered, and any other relevant references that you cite. The references should follow the format: Author names, “title”, Year, volume, first page – last page.
Use the following formatting guidelines: Font (arial or times new roman), font size 11. Margins 1 inch. Spacing: 1.08 lines. Please submit as .pdf. This report has a 3 page limit, including title and references.